Sıçanlarda Akut Kısıtlama ve Soğuk Kısıtlama Stres Tepkisinin Elektrokardiyografik Değerlendirmesi

Çağlasu Koç; Mehmet Ekici

doi:10.51755/turkvetj.1244382

EN TR

Electrocardiographic Evaluation of Acute Restraint and Cold Restraint Stress Response in Rats

Abstract

In this study, we investigated the effects of acute restraint stress and cold restraint stress on electrocardiographic (ECG) parameters in rats. A total of 18 male Wistar albino rats aged 8-10 weeks weighing 180-220 g were divided into three equal groups (n=6/group). No stressors were administered to the rats in the control group. The rats in the restraint group were kept in a restrainer for 2 hours. The rats in the cold restraint group were kept at +4°C for 2 hours in restrainer. ECG was recorded under ketamine and xylazine anesthesia in rats with the Televet II ECG device (Kruuse, Germany), and the Televet 100 program (version® 7.0.0, Kruuse, Heusenstamm, Germany) was used to analyze the leads II. There was no significant difference between the groups in the analysis of PR, QT, QRS intervals, and R-wave amplitude (p >0.05). However, the heart rate was significantly higher in the cold restraint group than in the control group (p <0.001) and restraint group (p <0.01). Conversely, the RR interval was significantly lower in the cold restraint group than in the control group (p <0.001) and restraint group (p <0.01). The QTc was increased in rats exposed to cold restraint stress compared to the control group (p <0.01) and restraint group (p <0.05). In conclusion, acute cold restraint stress may cause more pronounced ECG change than restraint stress.

Keywords

Destekleyen Kurum

TUBİTAK

Proje Numarası

2209- A - Üniversite Öğrencileri Araştırma Projeleri

Kaynakça

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Ayrıntılar

Birincil Dil

Türkçe

Konular

Veteriner Anatomi ve Fizyoloji

Bölüm

Araştırma Makalesi

Yazarlar

Çağlasu Koç
0000-0002-2925-6849
Türkiye

Mehmet Ekici ^*
0000-0002-2163-6214
Türkiye

Erken Görünüm Tarihi

28 Temmuz 2023

Yayımlanma Tarihi

31 Temmuz 2023

Gönderilme Tarihi

30 Ocak 2023

Kabul Tarihi

3 Mayıs 2023

Yayımlandığı Sayı

Yıl 1970 Cilt: 5 Sayı: 1

DOI

https://doi.org/10.51755/turkvetj.1244382

IZ

https://izlik.org/JA33AB53LN

Kaynak Göster

RIS / Bibtex

APA

Koç, Ç., & Ekici, M. (2023). Sıçanlarda Akut Kısıtlama ve Soğuk Kısıtlama Stres Tepkisinin Elektrokardiyografik Değerlendirmesi. Turkish Veterinary Journal, 5(1), 8-12. https://doi.org/10.51755/turkvetj.1244382

Sıçanlarda Akut Kısıtlama ve Soğuk Kısıtlama Stres Tepkisinin Elektrokardiyografik Değerlendirmesi

Electrocardiographic Evaluation of Acute Restraint and Cold Restraint Stress Response in Rats

Abstract

Keywords