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Comparison of autoanalyzer and blood gas device in creatinine and glucose analysis in lambs

Year 2022, , 42 - 45, 11.01.2023
https://doi.org/10.51755/turkvetj.1222016

Abstract

In this study, it was aimed to compare creatinine and glucose levels in blood samples taken from lambs by using autoanalyzer and blood gas device. 100 lambs of both sexes at the age of 1-3 months were included in the study. A 5 ml blood sample was taken once from the vena jugular of the lambs. Creatinine and glucose measurements were made from whole blood samples using a blood gas device and from serum samples in an autoanalyzer. There was a significant (p<0.05) difference between the devices in terms of creatinine and glucose levels. In addition, creatinine and glucose levels were found to have a significant correlation between the two devices (r=0.43 and r=0.974, p<0.001, respectively). As a result, it was concluded that there could be significant differences between the glucose and creatinine values of both devices and these differences should be evaluated in terms of analysis results.

References

  • Aydogdu U, Coskun A, Yuksel M, Basbug O, Agaoglu ZT (2018). The effect of dystocia on passive immune status, oxidative stress, venous blood gas and acid-base balance in lambs. Small Ruminant Research 166: 115-120.
  • Başbuğ O, Takcı A (2022). Evaluation of Clinical Accuracy of Portable Glucometers in Sheep at the Beginning of the Breeding Season. Van Vet J, 33 (3): 112-116. doi: https://doi.org/10.36483/vanvetj.1167136
  • Ekici M, Takcı A, Kıvrak MB (2021) Comparison of some hematological and serum biochemical variables in Kangal Akkaraman, Texel and Île De France ewes in lactation period within Sivas province. Eurasian J Vet Sci, 37(4): 296-302. doi 10.15312/EurasianJVetSci.2021.355
  • Kaneko JJ, Harvey JW, Bruss ML (2008) Clinical Biochemistry of Domestic Animals, Sixth Edition. Amsterdam: Elsevier, Academic Press, pp. 99, 306, 351-378, 618.
  • Karagul H, Altıntaş A, Fidancı UR, Sel T (2000) Klinik Biyokimya, Birinci Baskı, Ankara: Medisan Yayınevi, ss. 6-9. Kilgore ML, Steindel SJ, Smith JA (1999) Cost analysis for decision support: the case of comparing centralized versus distributed methods for blood gas testing. J Healthc Manag 44:207–15.
  • Kost GJ, Ehrmeyer SS, Chernow B, Winkelman JW, Zaloga GP, Dellinger RP, Shireyt T (1999) The laboratory-clinical interface: point-of-care testing. Chest 115:1140–54.
  • Luukkonen AAM, Lehto TM, Hedberg PSM, Vaskivuo TE (2016) Evaluation of a hand-held blood gas analyzer for rapid determination of blood gases, electrolytes and metabolites in intensive care setting. Clin Chem Lab Med 54(4):585-94. doi: 10.1515/cclm-2015-0592.
  • Mohammed-Ali Z, Bagherpoor S, Diker P, Hoang T, Vidovic I, Cursio C, Leung F, Brinc D (2020) Performance evaluation of all analytes on the epoc® Blood Analysis System for use in hospital surgical and intensive care units. Pract Lab Med 25;22:e00190. doi: 10.1016/j.plabm.2020.e00190.
  • Nichols JH, Kickler TS, Dyer KL, Humbertson SK, Cooper PC, Maughan WL, Oechsle DG (2000) Clinical outcomes of point-of-care testing in the interventional radiology and invasive cardiology setting. Clin Chem 46:543–50.
  • Price CP (2002) Medical and economic outcomes of point-of-care testing. Clin Chem Lab Med 40:246–51. Sacks DB (2012) Carbohydrates. In: Burtis CA, Ashwood ER, Bruns DE, editors. Tietz textbook of clinical chemistry and molecular diagnostics, 5th ed. St. Louis, MO: Elsevier Saundlers, pp709–30.
  • Schimke I (2009) Quality and timeliness in medical laboratory testing. Anal Bioanal Chem 2393:1499–504 Shin H, Lee I, Kim C, Choi HJ (2020) Point-of-care blood analysis of hypotensive patients in the emergency department Comparative Study Am J Emerg Med. 38(6):1049-1057. doi: 10.1016/j.ajem.2019.158363.
  • Turgut K (2000). Veteriner Klinik laboratuar Teşhis. 2. baskı. Bahçıvanlar baskı, Konya van der Heijden C, Roosens L, Cluckers H, Van Craenenbroeck AH, Peeters B (2019) Analytical and clinical performance of three hand-held point-of-care creatinine analyzers for renal function measurements prior to contrast-enhanced imaging. Clinica Chimica Acta 497: 13-19.

Kuzularda kreatinin ve glikoz analizlerinde otoanalizör ve kan gaz cihazının karşılaştırılması

Year 2022, , 42 - 45, 11.01.2023
https://doi.org/10.51755/turkvetj.1222016

Abstract

Bu çalışmada, kuzulardan alınan kan örneklerinde otoanalizör ve kan gaz cihazı kullanılarak kreatinin ve glikoz düzeylerinin karşılaştırılması amaçlandı. 1-3 aylık yaşta her iki cinsiyetten 100 kuzu çalışmaya dahil edildi. Kuzuların vena jugularisinden bir kez 5 ml kan örneği alındı. Alınan tam kan örneklerinden kan gaz cihazı kullanılarak ve serum örneklerinden otoanalizörde kreatinin ve glikoz ölçümleri yapıldı. Kreatinin ve glikoz düzeyleri açısından cihazlar arasında önemli düzeyde (p<0.05) farklılık belirlendi. Ayrıca kreatinin ve glikoz düzeylerinin iki cihaz arasında önemli korelasyona (sırasıyla r=0.43 ve r=0.974, p<0.001) sahip olduğu tespit edildi. Sonuç olarak, her iki cihazın glikoz ve kreatinin değerleri arasında önemli farklılıkların bulunabileceği ve analiz sonuçları açısından bu farklılıkların değerlendirilmesi gerektiği kanaatine varıldı.

References

  • Aydogdu U, Coskun A, Yuksel M, Basbug O, Agaoglu ZT (2018). The effect of dystocia on passive immune status, oxidative stress, venous blood gas and acid-base balance in lambs. Small Ruminant Research 166: 115-120.
  • Başbuğ O, Takcı A (2022). Evaluation of Clinical Accuracy of Portable Glucometers in Sheep at the Beginning of the Breeding Season. Van Vet J, 33 (3): 112-116. doi: https://doi.org/10.36483/vanvetj.1167136
  • Ekici M, Takcı A, Kıvrak MB (2021) Comparison of some hematological and serum biochemical variables in Kangal Akkaraman, Texel and Île De France ewes in lactation period within Sivas province. Eurasian J Vet Sci, 37(4): 296-302. doi 10.15312/EurasianJVetSci.2021.355
  • Kaneko JJ, Harvey JW, Bruss ML (2008) Clinical Biochemistry of Domestic Animals, Sixth Edition. Amsterdam: Elsevier, Academic Press, pp. 99, 306, 351-378, 618.
  • Karagul H, Altıntaş A, Fidancı UR, Sel T (2000) Klinik Biyokimya, Birinci Baskı, Ankara: Medisan Yayınevi, ss. 6-9. Kilgore ML, Steindel SJ, Smith JA (1999) Cost analysis for decision support: the case of comparing centralized versus distributed methods for blood gas testing. J Healthc Manag 44:207–15.
  • Kost GJ, Ehrmeyer SS, Chernow B, Winkelman JW, Zaloga GP, Dellinger RP, Shireyt T (1999) The laboratory-clinical interface: point-of-care testing. Chest 115:1140–54.
  • Luukkonen AAM, Lehto TM, Hedberg PSM, Vaskivuo TE (2016) Evaluation of a hand-held blood gas analyzer for rapid determination of blood gases, electrolytes and metabolites in intensive care setting. Clin Chem Lab Med 54(4):585-94. doi: 10.1515/cclm-2015-0592.
  • Mohammed-Ali Z, Bagherpoor S, Diker P, Hoang T, Vidovic I, Cursio C, Leung F, Brinc D (2020) Performance evaluation of all analytes on the epoc® Blood Analysis System for use in hospital surgical and intensive care units. Pract Lab Med 25;22:e00190. doi: 10.1016/j.plabm.2020.e00190.
  • Nichols JH, Kickler TS, Dyer KL, Humbertson SK, Cooper PC, Maughan WL, Oechsle DG (2000) Clinical outcomes of point-of-care testing in the interventional radiology and invasive cardiology setting. Clin Chem 46:543–50.
  • Price CP (2002) Medical and economic outcomes of point-of-care testing. Clin Chem Lab Med 40:246–51. Sacks DB (2012) Carbohydrates. In: Burtis CA, Ashwood ER, Bruns DE, editors. Tietz textbook of clinical chemistry and molecular diagnostics, 5th ed. St. Louis, MO: Elsevier Saundlers, pp709–30.
  • Schimke I (2009) Quality and timeliness in medical laboratory testing. Anal Bioanal Chem 2393:1499–504 Shin H, Lee I, Kim C, Choi HJ (2020) Point-of-care blood analysis of hypotensive patients in the emergency department Comparative Study Am J Emerg Med. 38(6):1049-1057. doi: 10.1016/j.ajem.2019.158363.
  • Turgut K (2000). Veteriner Klinik laboratuar Teşhis. 2. baskı. Bahçıvanlar baskı, Konya van der Heijden C, Roosens L, Cluckers H, Van Craenenbroeck AH, Peeters B (2019) Analytical and clinical performance of three hand-held point-of-care creatinine analyzers for renal function measurements prior to contrast-enhanced imaging. Clinica Chimica Acta 497: 13-19.
There are 12 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Surgery
Journal Section Research Article
Authors

Uğur Aydoğdu 0000-0002-9828-9863

Alparslan Coşkun 0000-0002-2242-9647

Onur Basbug 0000-0003-3136-0589

Sefer Türk 0000-0003-4683-5217

Zahid Tevfik Ağaoğlu 0000-0001-5707-405X

Publication Date January 11, 2023
Published in Issue Year 2022

Cite

APA Aydoğdu, U., Coşkun, A., Basbug, O., Türk, S., et al. (2023). Kuzularda kreatinin ve glikoz analizlerinde otoanalizör ve kan gaz cihazının karşılaştırılması. Turkish Veterinary Journal, 4(2), 42-45. https://doi.org/10.51755/turkvetj.1222016