Virüslerin Reverz Genetiği

Hasan Abaylı

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Virüslerin Reverz Genetiği

Öz

Reverz genetik, genom üzerindeki dizilerin fonksiyonlarını belirlemeye yönelik girişimlere imkan tanıyan güçlü sistemlerden oluşmaktadır. Virüslerin kolay manipüle edilebilir yapısı ve hızlı fenotipik karakter sergileme özelliği virüs reverz genetiği alanındaki gelişmeleri de beraberinde getirmiştir. Virüs reverz genetiği, özellikle dinamik yapısıyla mutasyon oluşturmaya müsait, yüksek patojenik RNA virüsleri hakkındaki bilinmezliklerin ortaya çıkarılmasında önemli görevler üstlenmektedir. Bu görevlerin başında viral patogenez ve virülens faktörlerin belirlenmesi sonrasında ise yüksek immunojenik, non-patojenik -iyi virüs- üretme girişimleri gelmektedir. Bu derlemede reverz genetik sistemler sistemleri ve mevcut gelişmeler hakkında bilgi verilmektedir.

Anahtar Kelimeler

Enfeksiyöz klon,kurtarma sistemleri,reverz genetik,virüs

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Details

Primary Language

Turkish

Subjects

Veterinary Surgery

Journal Section

Review

Authors

Hasan Abaylı ^*
0000-0003-2116-105X
Türkiye

Publication Date

August 15, 2019

Submission Date

March 22, 2019

Acceptance Date

August 16, 2019

Published in Issue

Year 2019 Volume: 1 Number: 2

IZ

https://izlik.org/JA29PC98EY

Cite

RIS / Bibtex

APA

Abaylı, H. (2019). Virüslerin Reverz Genetiği. Turkish Veterinary Journal, 1(2), 90-100. https://izlik.org/JA29PC98EY

Virüslerin Reverz Genetiği

Virüslerin Reverz Genetiği

Öz

Anahtar Kelimeler

Reverse Genetics of Viruses

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

IZ

Cite