Research Article

Epidemiology of Maedi-Visna Virus Infection in Kangal Akkaraman Sheep Raised in the Sivas Region

Volume: 7 Number: 2 December 29, 2025
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Epidemiology of Maedi-Visna Virus Infection in Kangal Akkaraman Sheep Raised in the Sivas Region

Abstract

Maedi-visna virus (MVV) is a retrovirus belonging to the Lentivirus genus that causes chronic and progressive disease in sheep with high global prevalence. This infection affects the respiratory and nervous systems of animals, leading to chronic pulmonary complications and neurological disorders. Currently, no therapeutic interventions or prophylactic vaccines are available for MVV infection. The objective of this study was to determine the seroprevalence of MVV infection in Kangal Akkaraman breed sheep raised in the Sivas region. Within the scope of the research, a total of 460 blood samples were collected using random sampling methodology, selecting five farms from each district across Sivas city center and ten districts. Commercial ELISA assay was employed for the detection of MVV antibodies. Serological analysis using ELISA revealed seropositivity in 228 out of 460 examined animals (49.6%). District-based seroprevalence rates demonstrated considerable variation, ranging from 13.04% (Gürün) to 82.60% (Gemerek). Age group analysis revealed a progressive increase in seropositivity rates with advancing age. Seropositivity was determined as 30% in male animals and 50% in female animals. Statistical evaluation indicated significant differences between districts and age groups (p<0.001 and p<0.05, respectively), while differences between farms and sexes did not demonstrate statistical significance (p>0.05). The obtained data indicate that Maedi-visna infection exhibits high prevalence in the Sivas region and may lead to substantial economic losses. This situation emphasizes the necessity for detailed investigation of the epidemiological characteristics of the disease, expansion of prevalence studies, and support of viral genotyping analyses through comprehensive field studies.

Keywords

Supporting Institution

CUBAP

Project Number

CÜBAP-V-2024-141

Ethical Statement

The study was conducted following approval from the Local Ethics Committee for Animal Experiments of Sivas Cumhuriyet University (Decision No: 65202830-050.04.04-63 Date: 29.03.2024)

Thanks

The authors would like to thank Sivas Cumhuriyet University Scientific Research Projects Coordination Unit for supporting this study as a Master's Thesis Project with project number V-2024-141.

References

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Details

Primary Language

English

Subjects

Veterinary Virology

Journal Section

Research Article

Publication Date

December 29, 2025

Submission Date

July 2, 2025

Acceptance Date

October 1, 2025

Published in Issue

Year 1970 Volume: 7 Number: 2

APA
Turan, T., & Yurt, U. F. (2025). Epidemiology of Maedi-Visna Virus Infection in Kangal Akkaraman Sheep Raised in the Sivas Region. Turkish Veterinary Journal, 7(2), 36-42. https://doi.org/10.51755/turkvetj.1709785