Analysis of Cerebrospinal Fluid Samples in Canine Tick Paralysis: Insights and Implications

Erdem Gülersoy; Canberk Balıkçı; Adem Şahan; İsmail Günal; Esma Kısmet; Ayfer Güllü Yücetepe; Ayda Nur Oğuz

doi:10.51755/turkvetj.1512638

EN TR

Analysis of Cerebrospinal Fluid Samples in Canine Tick Paralysis: Insights and Implications

Abstract

Tick paralysis, caused by the salivary neurotoxin of several species of ticks, is a non-infectious neurological syndrome. Its clinical findings are often confused with other acute flaccid paralyses (AFPs). Demographic data and cerebrospinal fluid (CSF) examination, along with routine analyses, can be used to increase the index of suspicion for tick paralysis. Thus, this study aims to elucidate neurological manifestations and mechanisms, offering diagnostic insights to enhance understanding of tick paralysis pathophysiology and inform treatment development and prevention. 15 dogs with tick paralysis and AFP findings were included. Anamnestic data were collected for all the dogs, followed by physical examination, complete blood count (CBC), and CSF examinations. It was observed that physical examination, CBC, and CSF analysis results were within reference values. Unexpectedly, despite the non-infectious nature of tick paralysis, Staphylococcus lentus and Aeromonas sobria were detected in three CSF samples. Although these bacteria are not typically associated with tick paralysis, their presence in shepherd dogs was interpreted as contamination from livestock. Consequently, it was noted that comprehensive evaluation of demographic data and other physical and laboratory findings may aid diagnosis in cases of tick paralysis, including atypical cases where ticks cannot be detected. It was concluded that while CSF analysis is diagnostically important for neurological disorders, careful consideration of contamination risk is warranted, especially in shepherd dogs.

Keywords

Köpek Kene Felcinde Beyin Omurilik Sıvısı Örneklerinin Analizi: Görüşler ve Çıkarımlar

Öz

Çeşitli kene türlerinin tükürük nörotoksininin neden olduğu kene felci, bulaşıcı olmayan bir nörolojik sendromdur. Klinik bulguları sıklıkla diğer akut flassid paralizilerle (AFP) karıştırılır. Rutin analizlerin yanı sıra demografik veriler ve beyin omurilik sıvısı (BOS) incelemesi, kene felci şüphesini artırmak için kullanılabilir. Bu nedenle, bu çalışma nörolojik bulguları ve mekanizmaları aydınlatmayı, kene felci patofizyolojisi anlayışını geliştirmek ve tedavi geliştirme ve önleme konusunda bilgi sağlamak için tanısal bilgiler sunmayı amaçlamaktadır. Kene felci ve AFP bulguları olan 15 köpek çalışmaya dahil edildi. Tüm köpeklerden anamnez verileri alındı, ardından fiziksel muayene, tam kan sayımı (CBC) ve BOS incelemeleri yapıldı. Fiziksel muayene, CBC ve BOS analiz sonuçlarının referans değerleri dahilinde olduğu görüldü. Kene felcinin bulaşıcı olmayan doğasına rağmen beklenmedik bir şekilde üç BOS örneğinde Staphylococcus lentus ve Aeromonas sobria tespit edildi. Her ne kadar bu bakteriler tipik olarak kene felci ile ilişkili olmasa da, çoban köpeklerinde bulunmaları çiftlik hayvanlarından kaynaklanan bir kontaminasyon olarak yorumlandı. Sonuç olarak, kenelerin tespit edilemediği atipik vakalar da dahil olmak üzere kene felci vakalarında demografik veriler ile diğer fiziksel ve laboratuvar bulgularının kapsamlı bir şekilde değerlendirilmesinin tanıya yardımcı olabileceği belirlendi. BOS analizinin nörolojik bozukluklarda tanısal açıdan önemli olduğu, özellikle çoban köpeklerinde kontaminasyon riskinin dikkatle değerlendirilmesi gerektiği sonucuna varıldı.

Anahtar Kelimeler

Ethical Statement

2022/003 – 01/06

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Details

Primary Language

English

Subjects

Veterinary Medicine , Veterinary Diagnosis and Diagnostics

Journal Section

Research Article

Authors

Erdem Gülersoy ^*
0000-0001-8511-0150
Türkiye

Canberk Balıkçı
0000-0001-7473-5163
Türkiye

Adem Şahan
0000-0002-4779-0893
Türkiye

İsmail Günal
0000-0003-3679-4132
Türkiye

Esma Kısmet
0000-0002-2906-074X
Türkiye

Ayfer Güllü Yücetepe
0000-0002-9842-3305
Türkiye

Ayda Nur Oğuz
0000-0002-0771-8029
Türkiye

Early Pub Date

December 28, 2024

Publication Date

December 31, 2024

Submission Date

July 8, 2024

Acceptance Date

November 4, 2024

Published in Issue

Year 2024 Volume: 6 Number: 2

DOI

https://doi.org/10.51755/turkvetj.1512638

IZ

https://izlik.org/JA23SA39KC

Cite

RIS / Bibtex

APA

Gülersoy, E., Balıkçı, C., Şahan, A., Günal, İ., Kısmet, E., Güllü Yücetepe, A., & Oğuz, A. N. (2024). Analysis of Cerebrospinal Fluid Samples in Canine Tick Paralysis: Insights and Implications. Turkish Veterinary Journal, 6(2), 42-48. https://doi.org/10.51755/turkvetj.1512638