Review
BibTex RIS Cite

Köpeklerde Prostat Hastalıkları: Etiyoloji, Tanı, Tedavi

Year 2023, Volume: 5 Issue: 1, 19 - 32, 31.07.2023

Mahir Kaya

https://doi.org/10.51755/turkvetj.1291777

Abstract

Köpeklerde yaygın görülen prostat hastalıkları bening prostat hiperplazisi, akut ve kronik prostatitis, prostat kistleri ve apsesi, prostat tümörleridir ve kastrasyon ile yakından ilişkilidirler. Pek çok olguda klinik bulguların asemptomatik veya non-spesifik olması teşhis edilmelerini güçleştir. Bu nedenle prostat hastalıkların prevalansı, tahmin edilenden daha yüksektir. En uygun medikal veya cerrahi tedaviye başlamak için kesin tanı şarttır. Bu derleme, sık karşılaşılan farklı prostat hastalıklarının etiyolojisini, klinik bulgularını, tanı yöntemlerini ve tedavi seçeneklerini son gelişmeleri içerecek şekilde aktarmayı amaçlamaktadır.

Keywords

Etiyoloji Köpek Prostat hastalıkları Tanı Tedavi

References

  • Albarellos GA, Montoya L, Waxman S, Kreil V, Ambros LA, Hallu R, Rebuelto M (2006). Ciprofloxacin and norfloxacin pharmacokinetics and prostatic fluid penetration in dogs after multiple oral dosing. Vet J 172(2): 334-339.
  • Alonge S, Melandri M, Aiudi G, Lacalandra GM (2018). Advances in prostatic diagnostics in Dogs: the role of canine prostatic spesific esterase in early diagnosis of prostatic disorders. Topic in Companion An Med 33(4): 105-108.
  • Atalan G, Holt PE, Barr FL, Brown PJ (1999). Ultrasonographic estimation of prostatic sizes in canine cadavers. Res Vet Sci 67(1): 7-15.
  • Axiak SM, Bigio A (2012). Canine prostatic carcinoma. Compend Contin Educ Vet 34(10): E1-E5.
  • Boland LE, Hardie RJ, Gregory SP, Lamb CR (2003). Ultrasound guided percutaneous drainage as the primary treatment for prostatic abscesses and cysts in dogs. J Am Anim Hosp Assoc 39(2): 151-159.
  • Bryan JN, Keeler MR, Henry CJ, Bryan ME, Hahn AW, Caldwell CW (2007). A population study of neutering status as a risk factor for canine prostate cancer. Prostate 67(11): 1174-1181.
  • Cazzuli G, Damian JP, Molina E, Pessina P (2021). Post-castration prostatic involution: a morphometric and endocrine study of healthy canines and those with benign prostatic hyperplasia. Reprod Dom Anim 57(2): 157-164.
  • Cristensen BW (2018). Canine prostat disease. Vet Clin Small Anim 48(4): 701-719.
  • Cunto M, Mariani E, Guido EA, Ballotta G, Zambelli D (2019). Clinical approach to prostatic diseases in the dog. Reprod Dom Anim 54(6): 815-822.
  • Das MR, Patra RC, Das RK, Rath PK, Mishra BP (2017). Hematobiochemical alterations and urinalysis in dogs suffering from benign prostatic hyperplasia. Vet. World 10(3): 331-335.
  • Evans HE, Christensen GC (1993). The urogenital system. In: Miller’s Anatomy of the Dog. Philadelphia, WB: Saunders. pp. 514–516.
  • Feeney DA, Johnston GR, Klausner JS, Perman V, Leininger JR, Tomlinson MJ (1987). Canine prostatic disease–comparison of radiographic appearance with morphologic and microbiologic findings: 30 cases (1981-1985). J Am Vet Med Assoc 190(8): 1018-1026.
  • Ferre-Dlocet L, Frigotto L, Contiero B, Bedin S, Romagnoli S (2022). Prostatic fluid composition and semen quality in dogs with benign prostatic hyperplasia undergoing tratment with osaterone acetate. Reprod Domest Anim 57(1): 72-79.
  • Foster RA (2012). Common lesions in the male reproductive tract of cats and dogs. Vet Clin North Am Small Anim Pract 42(3): 527-545.
  • Freitag T, Jerram RM, Walker AM, Warman CGA (2007). Surgical management of common canine prostatic conditions. Compend Contin Educ Vet 29(11): 656-658.
  • Gill SS, Barstad RD (2018). A review of the surgical management of perineal hernias in dogs. J Am Anim Hosp Assoc. 54(4): 179-187.
  • Gobello C, Corrada Y (2002). Noninfectious prostatic diseases in dogs. Compend Contin Ed Prac Vet 2, 99-108
  • Günzel-Apel AR, Möhrke C, Nautrup P (2001). Colour-code and pulse Doppler sonography of canine testis, epididimis and prostat gland:physiological and pathological findings. Reprod Dom Anim 36(5): 236-240.
  • Hecht S, Pollard R (2015). Male reproductive Tract. Atlas of Small animal ultrasonography. Penninck D, d’Anjou M (Eds) Wiley-Blackwell, pp: 423-455.
  • Holst BS, Holmroos E, Friling L, Hanas S, Langborg LM, Franko MA, Hansson K (2017). The association of between the serum concentration of canine specific esterase (CPSE) and the size of the canine prostate. Theriogenology. 93: 33-39.
  • Kamolpatana K, Johnston GR, Johnston SD (2000). Determination of canine prostatic volume using transabdominal ultrasonography. Vet Radiol Ultrasound 41(1): 73-77.
  • Kaya M, Şen Y, Bumin A (2012). Köpeklerde Prostat hastalıklarının Doppler ultrasonografi ile değerlendirilmesi. XIII. Vet Cer Kong, Kars, Türkiye, pp: 229-230.
  • Khadidja M, Adel A (2017). Canine prostatic disorders. Vet Med Open J 2(3): 83-90.
  • Kustritz MVR (2006). Collection of tissue and culture samples from the canine reproductive tract. Theriogenology 66(3): 567-574.
  • Leroy BE, Northrup N (2009). Prostate cancer in dogs: comparative and clinical aspects. Vet J 180(2): 149-162. Levy X, Nizanski W, Heimendahl A, Mimouni P (2014). Diagnosis of common prostatic conditions in dogs: an update. Reprod Dom Anim 49(2): 50-57.
  • L’Eplattenier HF, van Nimwegen SA, van Sluijs FJ, Kirpensteijn J (2006). Partial prostatectomy using Nd:YAG laser for management of canine prostate carcinoma. Vet Surg 35(4): 406-411.
  • Liptak JM, Brutscher SP, Monnet E, Dernall, WS, Twedt DC, Kazmierski KJ, Walter CU, Mullins MN, Larue SM, Withrow SJ (2004). Transurethral resection in the management of urethral and prostatic neoplasia in 6 dogs. Vet Surg 33(5): 505-516.
  • Luno V, Gonzalez N, Martinez F, Revert A, Morrell JM, Gil L (2020). Colloid centrifugation reduces bacterial load in chilled dog semen. Anim Reprod Sci 219: 106539.
  • Mango SD, Pisani G, Dondi F, Cinti F, Morello E, Martano M, Foglia A, Giacobino D, Buracco P (2021). Surgical treatment and outcome of sterile prostatic cysts in dogs. Vet Surg 50(5): 1009-1016.
  • Mantiaras G, Luvoni GC (2020). Advanced ultrasound techniques in small animals reproduction imaging. Reprod Dom Anim 55(2): 17-25.
  • Mantziaras G (2020). Imaging of the male reproductive tract: Not so easy as it looks like. Theriogenology 150: 490-497.
  • Mukaratirwa S, Chitura T (2007). Canine subclinical prostatic disease: histological prevalence and validity of digital rectal examination as a screening test. J S Afr Vet Assoc. 78(2): 66-68.
  • Mülazimoğlu SB, Beceriklisoy HB, Schäfer-Somi S, Kaya M, Bumin A, Özenç E, Gültekin N, Kanca H, Günen MZ, Kutsal O, Emre B, Aslan S (2016). B-mode echotexture analysis and color doppler sonography in canine mammary tumors. Kafkas Univ Vet Fak 22(6): 961-969.
  • Newell SM. Neuwirth L, Ginn PE, Roberts, GD, Prime LS, Harrison JM (1998). Doppler ultrasound of the prostate in normal dogs and in dogs with chronic lymphocytic-lymphoplasmocytic prostatitis. Vet Radiol Ultrasound 39(4): 332-336.
  • Nyland TG, Wallack ST, Wisner ER (2002). Needle-tract implantation following ultrasound-guided fine-needle aspiration biopsy of transitional cell carcinoma of the bladder, urethra and prostate. Vet Radiol Ultrasound 43(1): 50-53
  • Palmieri C, Fonseca-Alves CE, Laufer-Amorim R (2022). A review on canine and feline prostate pathology. Front Vet Sci 9: 881232
  • Polisca A, Troisi A, Fontaine E, Menchetti L, Fontbonne A (2016). A retrospective study of canine prostatic diseases from 2002 to 2009 at the Alfort Veterinary College in France. Theriogenology 85: 835-840 Powe JR, Canfield PJ, Martin PA (2004). Evaluation of the cytologic diagnosis of canine prostatic disorders. Vet Clin Pathol 33(3): 150-154.
  • Ruel Y, Barthez PY, Mailles A, Begon D (1998). Ultrasonographic evaluation of the prostate in healthy intact dogs. Vet Radiol Ultrasound 39(3): 212-216.
  • Ruetten H, Wehber M, Murphy M, Cole C, Sandhu S, Oakes S, Bjorling D, Waller K, Viviano K, Vezina C (2021). A retrospective review of canine benign prostatic hyperplasia with and without prostatitis. Clin Theriogenology. 13(4): 360-366.
  • Schäfer-Somi S (2022) Diseases of the Canine Prostate Gland. Recent Advances in Canine Medicine. doi: 10.5772/intechopen.105835.
  • Sirinarumitr K, Johnston SD, Kustritz MV, Johnston GR, Sarkar DK, Memon MA (2001). Effects of finasteride on size of the prostate gland and semen quality in dogs with benign prostatic hypertrophy. J Am Vet Med Assoc 218(8): 1275-1280.
  • Smith J (2008). Canine prostatic disease: a review of anatomy, pathology, diagnosis, and treatment. Theriogenology 70(3): 375-383.
  • Sorenmo KU, Goldschmidt MH, Shofer FS, Goldkamp C, Ferracone J (2004). Evaluation of cyclooxygenase‐1 and cyclooxygenase‐2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma. Vet Comp Oncol 2(1): 13-23.
  • Teske E, Naan EC, van Dijk EM, Van Garderen E, Schalken JA (2002). Canine prostate carcinoma: Epidemiological evidence of an increased risk in castrated dogs. Mol Cell Endocrinol 197(1-2): 251-255.
  • Tobias K (2017). Prostatic biopsy and prostatic omentalization. Manual of small animal soft tissue surgery. 2nd Ed. Wiley-Blackwell. pp: 255-264.
  • Wagenlehner FME, Weidner W, Sörgel F, Naber KG (2005). The role of antibiotics in chronic bacterial prostatitis. Int J Antimicrob Agents 26(1): 1-7.
  • Werhahn Beining F, Urhausen C, Wolf K, Schmicke M, Rohn K, Schuler G, Gunzel-Apel AR (2020). Rhodesian Ridgebacks have an increased risk to develop benign prostatic hyperplasia. Reprod Dom Anim 55(3): 283-292.
  • White RAS (2000). Prostatic surgery in the dog. Clin Tech Small Anim Pract 15(1): 46-51.

Canine Prostatic Disease: Etiology, Diagnosis, Treatment

Year 2023, Volume: 5 Issue: 1, 19 - 32, 31.07.2023

Mahir Kaya

https://doi.org/10.51755/turkvetj.1291777

Abstract

Common prostate diseases in dogs are benign prostatic hyperplasia, acute and chronic prostatitis, prostate cysts and abscess, prostate tumors and are closely related to castration. In many cases, clinical findings are asymptomatic or non-specific, making their diagnosis difficult. Therefore, the prevalence of prostatic diseases is higher than expected. A definitive diagnosis is essential in order to begin the most appropriate medical or surgical treatment. The aim of this review to lay down the etiology, clinical findings, diagnostic methods and treatment options of common prostate diseases, including the latest developments.

Keywords

Diagnosis Dog Etiyology Prostatic disease Treatment

References

  • Albarellos GA, Montoya L, Waxman S, Kreil V, Ambros LA, Hallu R, Rebuelto M (2006). Ciprofloxacin and norfloxacin pharmacokinetics and prostatic fluid penetration in dogs after multiple oral dosing. Vet J 172(2): 334-339.
  • Alonge S, Melandri M, Aiudi G, Lacalandra GM (2018). Advances in prostatic diagnostics in Dogs: the role of canine prostatic spesific esterase in early diagnosis of prostatic disorders. Topic in Companion An Med 33(4): 105-108.
  • Atalan G, Holt PE, Barr FL, Brown PJ (1999). Ultrasonographic estimation of prostatic sizes in canine cadavers. Res Vet Sci 67(1): 7-15.
  • Axiak SM, Bigio A (2012). Canine prostatic carcinoma. Compend Contin Educ Vet 34(10): E1-E5.
  • Boland LE, Hardie RJ, Gregory SP, Lamb CR (2003). Ultrasound guided percutaneous drainage as the primary treatment for prostatic abscesses and cysts in dogs. J Am Anim Hosp Assoc 39(2): 151-159.
  • Bryan JN, Keeler MR, Henry CJ, Bryan ME, Hahn AW, Caldwell CW (2007). A population study of neutering status as a risk factor for canine prostate cancer. Prostate 67(11): 1174-1181.
  • Cazzuli G, Damian JP, Molina E, Pessina P (2021). Post-castration prostatic involution: a morphometric and endocrine study of healthy canines and those with benign prostatic hyperplasia. Reprod Dom Anim 57(2): 157-164.
  • Cristensen BW (2018). Canine prostat disease. Vet Clin Small Anim 48(4): 701-719.
  • Cunto M, Mariani E, Guido EA, Ballotta G, Zambelli D (2019). Clinical approach to prostatic diseases in the dog. Reprod Dom Anim 54(6): 815-822.
  • Das MR, Patra RC, Das RK, Rath PK, Mishra BP (2017). Hematobiochemical alterations and urinalysis in dogs suffering from benign prostatic hyperplasia. Vet. World 10(3): 331-335.
  • Evans HE, Christensen GC (1993). The urogenital system. In: Miller’s Anatomy of the Dog. Philadelphia, WB: Saunders. pp. 514–516.
  • Feeney DA, Johnston GR, Klausner JS, Perman V, Leininger JR, Tomlinson MJ (1987). Canine prostatic disease–comparison of radiographic appearance with morphologic and microbiologic findings: 30 cases (1981-1985). J Am Vet Med Assoc 190(8): 1018-1026.
  • Ferre-Dlocet L, Frigotto L, Contiero B, Bedin S, Romagnoli S (2022). Prostatic fluid composition and semen quality in dogs with benign prostatic hyperplasia undergoing tratment with osaterone acetate. Reprod Domest Anim 57(1): 72-79.
  • Foster RA (2012). Common lesions in the male reproductive tract of cats and dogs. Vet Clin North Am Small Anim Pract 42(3): 527-545.
  • Freitag T, Jerram RM, Walker AM, Warman CGA (2007). Surgical management of common canine prostatic conditions. Compend Contin Educ Vet 29(11): 656-658.
  • Gill SS, Barstad RD (2018). A review of the surgical management of perineal hernias in dogs. J Am Anim Hosp Assoc. 54(4): 179-187.
  • Gobello C, Corrada Y (2002). Noninfectious prostatic diseases in dogs. Compend Contin Ed Prac Vet 2, 99-108
  • Günzel-Apel AR, Möhrke C, Nautrup P (2001). Colour-code and pulse Doppler sonography of canine testis, epididimis and prostat gland:physiological and pathological findings. Reprod Dom Anim 36(5): 236-240.
  • Hecht S, Pollard R (2015). Male reproductive Tract. Atlas of Small animal ultrasonography. Penninck D, d’Anjou M (Eds) Wiley-Blackwell, pp: 423-455.
  • Holst BS, Holmroos E, Friling L, Hanas S, Langborg LM, Franko MA, Hansson K (2017). The association of between the serum concentration of canine specific esterase (CPSE) and the size of the canine prostate. Theriogenology. 93: 33-39.
  • Kamolpatana K, Johnston GR, Johnston SD (2000). Determination of canine prostatic volume using transabdominal ultrasonography. Vet Radiol Ultrasound 41(1): 73-77.
  • Kaya M, Şen Y, Bumin A (2012). Köpeklerde Prostat hastalıklarının Doppler ultrasonografi ile değerlendirilmesi. XIII. Vet Cer Kong, Kars, Türkiye, pp: 229-230.
  • Khadidja M, Adel A (2017). Canine prostatic disorders. Vet Med Open J 2(3): 83-90.
  • Kustritz MVR (2006). Collection of tissue and culture samples from the canine reproductive tract. Theriogenology 66(3): 567-574.
  • Leroy BE, Northrup N (2009). Prostate cancer in dogs: comparative and clinical aspects. Vet J 180(2): 149-162. Levy X, Nizanski W, Heimendahl A, Mimouni P (2014). Diagnosis of common prostatic conditions in dogs: an update. Reprod Dom Anim 49(2): 50-57.
  • L’Eplattenier HF, van Nimwegen SA, van Sluijs FJ, Kirpensteijn J (2006). Partial prostatectomy using Nd:YAG laser for management of canine prostate carcinoma. Vet Surg 35(4): 406-411.
  • Liptak JM, Brutscher SP, Monnet E, Dernall, WS, Twedt DC, Kazmierski KJ, Walter CU, Mullins MN, Larue SM, Withrow SJ (2004). Transurethral resection in the management of urethral and prostatic neoplasia in 6 dogs. Vet Surg 33(5): 505-516.
  • Luno V, Gonzalez N, Martinez F, Revert A, Morrell JM, Gil L (2020). Colloid centrifugation reduces bacterial load in chilled dog semen. Anim Reprod Sci 219: 106539.
  • Mango SD, Pisani G, Dondi F, Cinti F, Morello E, Martano M, Foglia A, Giacobino D, Buracco P (2021). Surgical treatment and outcome of sterile prostatic cysts in dogs. Vet Surg 50(5): 1009-1016.
  • Mantiaras G, Luvoni GC (2020). Advanced ultrasound techniques in small animals reproduction imaging. Reprod Dom Anim 55(2): 17-25.
  • Mantziaras G (2020). Imaging of the male reproductive tract: Not so easy as it looks like. Theriogenology 150: 490-497.
  • Mukaratirwa S, Chitura T (2007). Canine subclinical prostatic disease: histological prevalence and validity of digital rectal examination as a screening test. J S Afr Vet Assoc. 78(2): 66-68.
  • Mülazimoğlu SB, Beceriklisoy HB, Schäfer-Somi S, Kaya M, Bumin A, Özenç E, Gültekin N, Kanca H, Günen MZ, Kutsal O, Emre B, Aslan S (2016). B-mode echotexture analysis and color doppler sonography in canine mammary tumors. Kafkas Univ Vet Fak 22(6): 961-969.
  • Newell SM. Neuwirth L, Ginn PE, Roberts, GD, Prime LS, Harrison JM (1998). Doppler ultrasound of the prostate in normal dogs and in dogs with chronic lymphocytic-lymphoplasmocytic prostatitis. Vet Radiol Ultrasound 39(4): 332-336.
  • Nyland TG, Wallack ST, Wisner ER (2002). Needle-tract implantation following ultrasound-guided fine-needle aspiration biopsy of transitional cell carcinoma of the bladder, urethra and prostate. Vet Radiol Ultrasound 43(1): 50-53
  • Palmieri C, Fonseca-Alves CE, Laufer-Amorim R (2022). A review on canine and feline prostate pathology. Front Vet Sci 9: 881232
  • Polisca A, Troisi A, Fontaine E, Menchetti L, Fontbonne A (2016). A retrospective study of canine prostatic diseases from 2002 to 2009 at the Alfort Veterinary College in France. Theriogenology 85: 835-840 Powe JR, Canfield PJ, Martin PA (2004). Evaluation of the cytologic diagnosis of canine prostatic disorders. Vet Clin Pathol 33(3): 150-154.
  • Ruel Y, Barthez PY, Mailles A, Begon D (1998). Ultrasonographic evaluation of the prostate in healthy intact dogs. Vet Radiol Ultrasound 39(3): 212-216.
  • Ruetten H, Wehber M, Murphy M, Cole C, Sandhu S, Oakes S, Bjorling D, Waller K, Viviano K, Vezina C (2021). A retrospective review of canine benign prostatic hyperplasia with and without prostatitis. Clin Theriogenology. 13(4): 360-366.
  • Schäfer-Somi S (2022) Diseases of the Canine Prostate Gland. Recent Advances in Canine Medicine. doi: 10.5772/intechopen.105835.
  • Sirinarumitr K, Johnston SD, Kustritz MV, Johnston GR, Sarkar DK, Memon MA (2001). Effects of finasteride on size of the prostate gland and semen quality in dogs with benign prostatic hypertrophy. J Am Vet Med Assoc 218(8): 1275-1280.
  • Smith J (2008). Canine prostatic disease: a review of anatomy, pathology, diagnosis, and treatment. Theriogenology 70(3): 375-383.
  • Sorenmo KU, Goldschmidt MH, Shofer FS, Goldkamp C, Ferracone J (2004). Evaluation of cyclooxygenase‐1 and cyclooxygenase‐2 expression and the effect of cyclooxygenase inhibitors in canine prostatic carcinoma. Vet Comp Oncol 2(1): 13-23.
  • Teske E, Naan EC, van Dijk EM, Van Garderen E, Schalken JA (2002). Canine prostate carcinoma: Epidemiological evidence of an increased risk in castrated dogs. Mol Cell Endocrinol 197(1-2): 251-255.
  • Tobias K (2017). Prostatic biopsy and prostatic omentalization. Manual of small animal soft tissue surgery. 2nd Ed. Wiley-Blackwell. pp: 255-264.
  • Wagenlehner FME, Weidner W, Sörgel F, Naber KG (2005). The role of antibiotics in chronic bacterial prostatitis. Int J Antimicrob Agents 26(1): 1-7.
  • Werhahn Beining F, Urhausen C, Wolf K, Schmicke M, Rohn K, Schuler G, Gunzel-Apel AR (2020). Rhodesian Ridgebacks have an increased risk to develop benign prostatic hyperplasia. Reprod Dom Anim 55(3): 283-292.
  • White RAS (2000). Prostatic surgery in the dog. Clin Tech Small Anim Pract 15(1): 46-51.
There are 48 citations in total.

Details

Primary Language Turkish
Subjects Veterinary Surgery
Journal Section Review
Authors

Mahir Kaya 0000-0002-2979-8832

Early Pub Date July 28, 2023
Publication Date July 31, 2023
Published in Issue Year 2023Volume: 5 Issue: 1

Cite

APA Kaya, M. (2023). Köpeklerde Prostat Hastalıkları: Etiyoloji, Tanı, Tedavi. Turkish Veterinary Journal, 5(1), 19-32. https://doi.org/10.51755/turkvetj.1291777
 Download Cover Image