Research Article
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Metabolic Profile in Dairy Cattle with Displacement of the Abomasum

Year 2022, Volume: 4 Issue: 1, 18 - 23, 23.12.2022

Alparslan Coşkun , Uğur Aydoğdu , Hasan Guzelbektes , İsmail Şen

https://doi.org/10.51755/turkvetj.1172715

Abstract

The objective of this research was to evaluation metabolic, biochemical and hematological parameters in dairy cattle with displacement of the abomasum (DA). In this study, 80 dairy cattle with DA and 10 healthy dairy cattle in early lactation were used. Jugular venous blood samples for blood gases, hematological parameters and serum biochemical analysis of all cattle were taken. Glucose, lactate, triglycerides, BHB, NEFA, insulin, VLDL, GGT, CK concentrations and pH and hematocrit value of cattle with DA were significantly (P<0.05) higher compared to control cattle. Whereas cholesterol, total protein, Na+, K+ and iCa+2 levels in dairy cattle with DA were significantly (P<0.05) decreased compared to control cattle. In conclusion, displacement of the abomasum is usually associated with hemoconcentration, electrolyte and energy imbalance, and disturbances in hepatic function.

Keywords

Dairy cattle displacement of the abomasum metabolic profile

Supporting Institution

This work was supported by the Sivas Cumhuriyet University Scientific Research Projects Coordinator.

Project Number

V004

Thanks

Presented in part in abstract form at the 11. Veterinary Internal Diseases Congress Samsun, Turkey, May 21-24, 2015

References

  • 1. Bartlett PC, Kopcha M, Coe PH, Ames NK, Ruegg PL, Erskine RJ (1995) Economic comparison of the pyloro-omentopexy vs the roll-and-toggle procedure for treatment of left displacement of the abomasum in dairy cattle. JAVMA 206(8):1156-1162.
  • 2. Basoglu A, Baspinar N, Tenori L, Licari C and Gulersoy E (2020) Nuclear magnetic resonance (NMR)-based metabolome profile evaluation in dairy cows with and without displaced abomasum. Vet Q 40(1):1–15. https://doi.org/10.1080/01652176.2019.1707907
  • 3. Chapinal N, Carson M, Duffield TF, Capel M, Godden S, Overton M, Santos JE, LeBlanc SJ (2011) The association of serum metabolites with clinical disease during the transition period. J Dairy Sci 94(10):4897-903. https://doi.org/10.3168/jds.2010-4075
  • 4. Civelek T, Sevinç M (2003) Sütçü Sığırların Periparturient Dönem Hastalıklarında Serum Apolipoprotein B-100 Konsantrasyonları. Vet Bil Derg 19(1-2):81-92.
  • 5. Constable PD, Hinchcliff KW, Done SH, Grünberg W (2018) Veterinary Medicine. A textbook of the diseases of cattle, horses, sheep, pigs, and goats. 11th ed., Saunders Ltd, Philadelphia.
  • 6. Constable PD, Miller GY, Hoffsis GF, Hull BL, Rings DM (1992) Risk factors for abomasal volvulus and left abomasal displacement in cattle. Am J Vet Res 53:1184-1191.
  • 7. Dezfouli MM, Eftekhari Z, Sadeghian S, Bahounar A, Jeloudari M (2013) Evaluation of hematological and biochemical profiles in dairy cows with left displacement of the abomasum. Comp Clin Path 22(2):175-179. https://doi.org/10.1007/s00580-011-1382-5
  • 8. Doll K, Sickinger M, Seeger T 2009 New aspects in the pathogenesis of abomasal displacement. Vet J 181:90-96. https://doi.org/10.1016/j.tvjl.2008.01.013
  • 9. Durgut R, Sagkan Ozturk A, Ozturk OH, Guzel M (2016) Evaluation of oxidative stress, antioxidant status and lipid profile in cattle with displacement of the abomasum. Ankara Üniv Vet Fak Derg 63:137-141.
  • 10. Fubini SL, Gran YT, Smith DF (1991) Right displacement of the abomasum or abomasal volvulus in dairy cows: 458 cases (1980-1987). J Am Vet Assoc 198:460-464.
  • 11. Fürll M (2002) Stoffwechselstörungen bei Wiederkaüern: Erkennung– Behandeln – Vorbeugen. Leipzig.
  • 12. Geishauser T (1995) Abomasal displacement in the bovine-A review on character, occurrence, aetiology and pathogenesis. Zentralbl Veterinarmed A 42: 229-251.
  • 13. Geishauser T, Leslie K, Duffield T (2000) Metabolic aspects in the etiology of displaced abomasum. Vet Clin North Am Food Anim Pract 16(2): 255-265. https://doi.org/10.1016/s0749-0720(15)30104-3
  • 14. Grünberg W, Constable PD, Schröder U, Staufenbiel R, Morin D, Rohn M (2005) Phoshorus homestasis indairy cow with abomasal displacement or abomasal volvulus. J Vet Intern Med 219:894-898. https://doi.org/10.1892/0891-6640(2005)19[894:phidcw]2.0.co;2
  • 15. Guard C (1996) Diseases of the alimentary tract, Smith BP (Ed) In: Large Animal Internal Medicine, second edition, Mosby, St Louis, pp: 868-884.
  • 16. Guard C. (1990). Abomasal displacement and volvulus. Smith BP (Ed) In: Large animal internal medicine, Mosby, St Louis, pp.792–797.
  • 17. Guzelbektes H, Sen I, Ok M, Constable PD, Boydak M, Coskun A (2010) Serum amyloid A and haptoglobin concentrations and liver fat percentage in lactating dairy cows with abomasal displacement. J Vet Intern Med 24(1):213-219. https://doi.org/10.1111/j.1939-1676.2009.0444.x
  • 18. Hamana M, Ohtsuka H, Oikawa M, Kawamura S (2010) Blood free amino acids in the postpartum dairy cattle with left displaced abomasum. J Vet Med Sci 72(10): 1355-1358. https://doi.org/10.1292/jvms.09-0239
  • 19. Herdt TH (2000) Ruminant adaptation to negative energy balance. Influences on the etiology of ketosis and fatty liver. Vet Clin North Am: Food Anim Prac 16:215-230. https://doi.org/10.1016/s0749-0720(15)30102-x
  • 20. Jorgensen RJ, Nyengaard NR, Hara S, Enemark JM, Andersen PH (1998) Rumen motility during induced hyper- and hypocalcaemia. Acta Vet Scand 39: 331-338. https://doi.org/10.1186/BF03547781
  • 21. Katoh N (2002) Relevance of Apo lipoproteins in the development of fatty liver and fatty liver-related peripartum disease in dairy cows. J Vet Med Sci 64:293-307. https://doi.org/10.1292/jvms.64.293
  • 22. Klevenhusen F, Humer E, Metzler-Zebeli B, Podstatzky-Lichtenstein L, Wittek T, Zebeli Q (2015) Metabolic profile and inflammatory responses in dairy cows with left displaced abomasum kept under small-scaled farm conditions. Animals (Basel) 5(4):1021-1033. https://doi.org/10.3390/ani5040396
  • 23. LeBlanc SJ, Leslie KE, Duffield TF (2005) Metabolic predictors of displaced abomasum in dairy cattle. J Dairy Sci 88:159-170. https://doi.org/10.3168/jds.S0022-0302(05)72674-6
  • 24. Leblanc SJ (2010) Monitoring metabolic health of dairy cattle in the transition period. J Reprod Dev 56:29-35. https://doi.org/10.1262/jrd.1056s29
  • 25. Madison JB, Troutt HF (1988) Effects of hypocalcaemia on abomasal motility. Res Vet Sci 44: 264-266.
  • 26. Momke S, Sickinger M, Rehage J, Doll K, Distl O (2012) Transcription factor binding site polymorphism in the motilin gene associated with left-sided displacement of the abomasum in German Holstein cattle. PLoS One 7(4):e35562. https://doi.org/10.1371/journal.pone.0035562
  • 27. Pravettoni D, Doll K, Hummel M, Cavallone E, Re M, Belloli AG (2004) Insulin resistance and abomasal motility disorders in cows detected by use of abomasoduodenal electromyography after surgical correction of left displaced abomasum. Am J Vet Res 65:1319-1324. https://doi.org/10.2460/ajvr.2004.65.1319
  • 28. Sattler T, Fürll M (2004) Creatine kinase and aspartate aminotransferase in cows as indicators for endometritis. J Vet Med A Physiol Pathol Clin Med 51(3):132-137. https://doi.org/10.1111/j.1439-0442.2004.00612.x
  • 29. Seifi HA, Leblanc SJ, Leslie KE, Duffield TF (2011) Metabolic predictors of post-partum disease and culling risk in dairy cattle. Vet J 188(2):216-220. https://doi.org/10.1016/j.tvjl.2010.04.007
  • 30. Sen I, Wittek T, Guzelbektes H (2015) Metabolic indicators and risk factors of left displaced abomasum in dairy cattle. Eurasian J Vet Sci 31(2):63-69. https://doi.org/10.15312/EurasianJVetSci.2015210076
  • 31. Sen I, Ok M, Coskun A (2006) The level of serum ionised calcium, aspartate aminotransferase, insulin, glucose, betahydroxybutyrate concentrations and blood gas parameters in cows with left displacement of abomasum. Pol J Vet Sci 9(4):227-232.
  • 32. Sen I, Ok M, Turgut K, Birdane FM, Guzelbektas H (2002) Role of gastrin in the aetiology of abomasal displacement in dairy cows. Vet Rec 151(1): 26-27. https://doi.org/10.1136/vr.151.1.26
  • 33. Sevinç M, Basoğlu A, Güzelbekteş H, Boydak M (2003) Lipid and lipoprotein levels in dairy cows with fatty liver. Turk J Vet Anim Sci 27: 295-299.
  • 34. Sevinc M, Ok M, Basoglu A (2002) Liver function in dairy cows with abomasal displacement. Revue Méd Vét 153(7):477-480.
  • 35. Smith BP (2009) Large animal Internal Medicine. 4th ed, St Louis, Missouri, pp. 857-860.
  • 36. Song Y, Loor JJ, Zhao C, Huang D, Du X, Li X, Wang Z, Liu G, Li X (2020) Potential hemo-biological identification markers to the left displaced abomasum in dairy cows. BMC Vet Res 16:470. https://doi.org/10.1186/s12917-020-02676-x
  • 37. Stengarde L, Holtenius K, Traven M, Hultgren J, Niskanen R, Emanuelson U (2010) Blood profiles in dairy cows with displaced abomasum. J Dairy Sci 93(10):4691-4699. https://doi.org/10.3168/jds.2010-3295
  • 38. Stengärde LU, Pehrson BG (2002) Effects of management, feeding, and treatment on clinical and biochemical variables in cattle with displaced abomasum. Am J Vet Res 63:137-142. https://doi.org/10.2460/ajvr.2002.63.137
  • 39. Van Winden SCL, Kuiper R (2003) Left displacement of the abomasum in dairy cattle: recent developments in epidemiological and etiological aspects. Vet Res 34: 47-56. https://doi.org/10.1051/vetres:2002060
  • 40. Ward JL, Smith DF, Fubini SL, Deuel-Armando DN (1994) Evaluation of abomasal outflow diversion as an experimental model of hypochloremic, hypokalemic metabolic alkalosis in lactating cows. Can J Vet Res 58:13–19.
  • 41. Yurdakul İ, Aydoğdu U (2018) The right displacement of the abomasum complicated with abomasitis in a calf. Ankara Üniv Vet Fak Derg 65:433-437.
  • 42. Zadnik T (2003) A comparative study of the hematobiochemical parameters between clinically healthy cows and cows with displacement of the abomasum. Acta Vet (Beograd) 53(5-6):297-309. https://doi.org/10.2298/AVB0306297Z

Abomasum Deplasmanlı Süt Sığırlarında Metabolik Profil

Year 2022, Volume: 4 Issue: 1, 18 - 23, 23.12.2022

Alparslan Coşkun , Uğur Aydoğdu , Hasan Guzelbektes , İsmail Şen

https://doi.org/10.51755/turkvetj.1172715

Abstract

Bu araştırmanın amacı, abomazum deplasmanlı (AD) süt sığırlarında metabolik, biyokimyasal ve hematolojik parametreleri değerlendirmektir. Bu çalışmada AD'lı 80 süt sığırı ve erken laktasyonda 10 sağlıklı süt sığırı kullanıldı. Tüm sığırlardan kan gazları, hematolojik parametreler ve serum biyokimyasal analizleri için juguler venöz kan örnekleri alındı. Abomazum deplasmanlıı sığırların glukoz, laktat, trigliseritler, BHB, NEFA, insülin, VLDL, GGT, CK konsantrasyonları ile pH ve hematokrit değerleri kontrol sığırlarına göre önemli ölçüde (P<0.05) yüksek bulundu. Aksine, AD’lı süt sığırlarında kolesterol, total protein, Na+, K+ ve iCa+2 seviyeleri kontrol sığırlarına göre önemli ölçüde (P<0.05) düşüktü. Sonuç olarak, abomazumun deplasmanı genellikle hemokonsantrasyon, elektrolit ve enerji dengesizliği ve hepatik fonksiyon bozuklukları ile ilişkilidir.

Keywords

Süt sığırı abomazumun deplasmanı metabolik profil

Project Number

V004

References

  • 1. Bartlett PC, Kopcha M, Coe PH, Ames NK, Ruegg PL, Erskine RJ (1995) Economic comparison of the pyloro-omentopexy vs the roll-and-toggle procedure for treatment of left displacement of the abomasum in dairy cattle. JAVMA 206(8):1156-1162.
  • 2. Basoglu A, Baspinar N, Tenori L, Licari C and Gulersoy E (2020) Nuclear magnetic resonance (NMR)-based metabolome profile evaluation in dairy cows with and without displaced abomasum. Vet Q 40(1):1–15. https://doi.org/10.1080/01652176.2019.1707907
  • 3. Chapinal N, Carson M, Duffield TF, Capel M, Godden S, Overton M, Santos JE, LeBlanc SJ (2011) The association of serum metabolites with clinical disease during the transition period. J Dairy Sci 94(10):4897-903. https://doi.org/10.3168/jds.2010-4075
  • 4. Civelek T, Sevinç M (2003) Sütçü Sığırların Periparturient Dönem Hastalıklarında Serum Apolipoprotein B-100 Konsantrasyonları. Vet Bil Derg 19(1-2):81-92.
  • 5. Constable PD, Hinchcliff KW, Done SH, Grünberg W (2018) Veterinary Medicine. A textbook of the diseases of cattle, horses, sheep, pigs, and goats. 11th ed., Saunders Ltd, Philadelphia.
  • 6. Constable PD, Miller GY, Hoffsis GF, Hull BL, Rings DM (1992) Risk factors for abomasal volvulus and left abomasal displacement in cattle. Am J Vet Res 53:1184-1191.
  • 7. Dezfouli MM, Eftekhari Z, Sadeghian S, Bahounar A, Jeloudari M (2013) Evaluation of hematological and biochemical profiles in dairy cows with left displacement of the abomasum. Comp Clin Path 22(2):175-179. https://doi.org/10.1007/s00580-011-1382-5
  • 8. Doll K, Sickinger M, Seeger T 2009 New aspects in the pathogenesis of abomasal displacement. Vet J 181:90-96. https://doi.org/10.1016/j.tvjl.2008.01.013
  • 9. Durgut R, Sagkan Ozturk A, Ozturk OH, Guzel M (2016) Evaluation of oxidative stress, antioxidant status and lipid profile in cattle with displacement of the abomasum. Ankara Üniv Vet Fak Derg 63:137-141.
  • 10. Fubini SL, Gran YT, Smith DF (1991) Right displacement of the abomasum or abomasal volvulus in dairy cows: 458 cases (1980-1987). J Am Vet Assoc 198:460-464.
  • 11. Fürll M (2002) Stoffwechselstörungen bei Wiederkaüern: Erkennung– Behandeln – Vorbeugen. Leipzig.
  • 12. Geishauser T (1995) Abomasal displacement in the bovine-A review on character, occurrence, aetiology and pathogenesis. Zentralbl Veterinarmed A 42: 229-251.
  • 13. Geishauser T, Leslie K, Duffield T (2000) Metabolic aspects in the etiology of displaced abomasum. Vet Clin North Am Food Anim Pract 16(2): 255-265. https://doi.org/10.1016/s0749-0720(15)30104-3
  • 14. Grünberg W, Constable PD, Schröder U, Staufenbiel R, Morin D, Rohn M (2005) Phoshorus homestasis indairy cow with abomasal displacement or abomasal volvulus. J Vet Intern Med 219:894-898. https://doi.org/10.1892/0891-6640(2005)19[894:phidcw]2.0.co;2
  • 15. Guard C (1996) Diseases of the alimentary tract, Smith BP (Ed) In: Large Animal Internal Medicine, second edition, Mosby, St Louis, pp: 868-884.
  • 16. Guard C. (1990). Abomasal displacement and volvulus. Smith BP (Ed) In: Large animal internal medicine, Mosby, St Louis, pp.792–797.
  • 17. Guzelbektes H, Sen I, Ok M, Constable PD, Boydak M, Coskun A (2010) Serum amyloid A and haptoglobin concentrations and liver fat percentage in lactating dairy cows with abomasal displacement. J Vet Intern Med 24(1):213-219. https://doi.org/10.1111/j.1939-1676.2009.0444.x
  • 18. Hamana M, Ohtsuka H, Oikawa M, Kawamura S (2010) Blood free amino acids in the postpartum dairy cattle with left displaced abomasum. J Vet Med Sci 72(10): 1355-1358. https://doi.org/10.1292/jvms.09-0239
  • 19. Herdt TH (2000) Ruminant adaptation to negative energy balance. Influences on the etiology of ketosis and fatty liver. Vet Clin North Am: Food Anim Prac 16:215-230. https://doi.org/10.1016/s0749-0720(15)30102-x
  • 20. Jorgensen RJ, Nyengaard NR, Hara S, Enemark JM, Andersen PH (1998) Rumen motility during induced hyper- and hypocalcaemia. Acta Vet Scand 39: 331-338. https://doi.org/10.1186/BF03547781
  • 21. Katoh N (2002) Relevance of Apo lipoproteins in the development of fatty liver and fatty liver-related peripartum disease in dairy cows. J Vet Med Sci 64:293-307. https://doi.org/10.1292/jvms.64.293
  • 22. Klevenhusen F, Humer E, Metzler-Zebeli B, Podstatzky-Lichtenstein L, Wittek T, Zebeli Q (2015) Metabolic profile and inflammatory responses in dairy cows with left displaced abomasum kept under small-scaled farm conditions. Animals (Basel) 5(4):1021-1033. https://doi.org/10.3390/ani5040396
  • 23. LeBlanc SJ, Leslie KE, Duffield TF (2005) Metabolic predictors of displaced abomasum in dairy cattle. J Dairy Sci 88:159-170. https://doi.org/10.3168/jds.S0022-0302(05)72674-6
  • 24. Leblanc SJ (2010) Monitoring metabolic health of dairy cattle in the transition period. J Reprod Dev 56:29-35. https://doi.org/10.1262/jrd.1056s29
  • 25. Madison JB, Troutt HF (1988) Effects of hypocalcaemia on abomasal motility. Res Vet Sci 44: 264-266.
  • 26. Momke S, Sickinger M, Rehage J, Doll K, Distl O (2012) Transcription factor binding site polymorphism in the motilin gene associated with left-sided displacement of the abomasum in German Holstein cattle. PLoS One 7(4):e35562. https://doi.org/10.1371/journal.pone.0035562
  • 27. Pravettoni D, Doll K, Hummel M, Cavallone E, Re M, Belloli AG (2004) Insulin resistance and abomasal motility disorders in cows detected by use of abomasoduodenal electromyography after surgical correction of left displaced abomasum. Am J Vet Res 65:1319-1324. https://doi.org/10.2460/ajvr.2004.65.1319
  • 28. Sattler T, Fürll M (2004) Creatine kinase and aspartate aminotransferase in cows as indicators for endometritis. J Vet Med A Physiol Pathol Clin Med 51(3):132-137. https://doi.org/10.1111/j.1439-0442.2004.00612.x
  • 29. Seifi HA, Leblanc SJ, Leslie KE, Duffield TF (2011) Metabolic predictors of post-partum disease and culling risk in dairy cattle. Vet J 188(2):216-220. https://doi.org/10.1016/j.tvjl.2010.04.007
  • 30. Sen I, Wittek T, Guzelbektes H (2015) Metabolic indicators and risk factors of left displaced abomasum in dairy cattle. Eurasian J Vet Sci 31(2):63-69. https://doi.org/10.15312/EurasianJVetSci.2015210076
  • 31. Sen I, Ok M, Coskun A (2006) The level of serum ionised calcium, aspartate aminotransferase, insulin, glucose, betahydroxybutyrate concentrations and blood gas parameters in cows with left displacement of abomasum. Pol J Vet Sci 9(4):227-232.
  • 32. Sen I, Ok M, Turgut K, Birdane FM, Guzelbektas H (2002) Role of gastrin in the aetiology of abomasal displacement in dairy cows. Vet Rec 151(1): 26-27. https://doi.org/10.1136/vr.151.1.26
  • 33. Sevinç M, Basoğlu A, Güzelbekteş H, Boydak M (2003) Lipid and lipoprotein levels in dairy cows with fatty liver. Turk J Vet Anim Sci 27: 295-299.
  • 34. Sevinc M, Ok M, Basoglu A (2002) Liver function in dairy cows with abomasal displacement. Revue Méd Vét 153(7):477-480.
  • 35. Smith BP (2009) Large animal Internal Medicine. 4th ed, St Louis, Missouri, pp. 857-860.
  • 36. Song Y, Loor JJ, Zhao C, Huang D, Du X, Li X, Wang Z, Liu G, Li X (2020) Potential hemo-biological identification markers to the left displaced abomasum in dairy cows. BMC Vet Res 16:470. https://doi.org/10.1186/s12917-020-02676-x
  • 37. Stengarde L, Holtenius K, Traven M, Hultgren J, Niskanen R, Emanuelson U (2010) Blood profiles in dairy cows with displaced abomasum. J Dairy Sci 93(10):4691-4699. https://doi.org/10.3168/jds.2010-3295
  • 38. Stengärde LU, Pehrson BG (2002) Effects of management, feeding, and treatment on clinical and biochemical variables in cattle with displaced abomasum. Am J Vet Res 63:137-142. https://doi.org/10.2460/ajvr.2002.63.137
  • 39. Van Winden SCL, Kuiper R (2003) Left displacement of the abomasum in dairy cattle: recent developments in epidemiological and etiological aspects. Vet Res 34: 47-56. https://doi.org/10.1051/vetres:2002060
  • 40. Ward JL, Smith DF, Fubini SL, Deuel-Armando DN (1994) Evaluation of abomasal outflow diversion as an experimental model of hypochloremic, hypokalemic metabolic alkalosis in lactating cows. Can J Vet Res 58:13–19.
  • 41. Yurdakul İ, Aydoğdu U (2018) The right displacement of the abomasum complicated with abomasitis in a calf. Ankara Üniv Vet Fak Derg 65:433-437.
  • 42. Zadnik T (2003) A comparative study of the hematobiochemical parameters between clinically healthy cows and cows with displacement of the abomasum. Acta Vet (Beograd) 53(5-6):297-309. https://doi.org/10.2298/AVB0306297Z
There are 42 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section Research Article
Authors

Alparslan Coşkun 0000-0002-2242-9647

Uğur Aydoğdu 0000-0002-9828-9863

Hasan Guzelbektes 0000-0002-0227-0691

İsmail Şen 0000-0002-2965-7183

Project Number V004
Early Pub Date December 24, 2022
Publication Date December 23, 2022
Published in Issue Year 2022Volume: 4 Issue: 1

Cite

APA Coşkun, A., Aydoğdu, U., Guzelbektes, H., Şen, İ. (2022). Metabolic Profile in Dairy Cattle with Displacement of the Abomasum. Turkish Veterinary Journal, 4(1), 18-23. https://doi.org/10.51755/turkvetj.1172715
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