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Primer Diffuse Iris Melanoma

Year 2019, Volume: 16 Issue: 2, 154 - 157, 08.08.2019
https://doi.org/10.32707/ercivet.595598

Abstract

Early
diagnosis of diffuse iris melanoma is a very important due to the potential
risk of enucleation, metastasis and loss of functional vision. It may occur as
a focal or diffuse lession in both eyes. Treatment of the disease varietes
according to the age, clinical condition of the patient, the number and size of
iridal pigment areas, grownth rate of the tumor, and incidense of glaucoma with
chronic üveitis. The material of the study consisted of an eigth-year-old,
non-sterilized, male, medium-haired cat. The cat had pigmentation and
buphthalmos in the iris of the left eye for approximately one year. Clinical
examination revealed diffuse thickening of the iris of the left eye, dark brown
pigmentation, pupillary occlusion, secondary glaucoma. In the treatment, the
bulbus oculi removed from the orbit by the method of enucleation bulbi and sent
for histopathologic examination. According to the histopathological
examination, this hyperpigmentation of the iris is diagnosed as diffuse iris
melanoma. There isn’t any metastasic findings during the one year follow-up of
the patient.

References

  • 1. Beton A, Healy LN, English RV, Bunch SE. Atypical limbal melanoma in a cat. J Vet Intern Med 1999; 13(4): 379-81.
  • 2. Baptista CS, de Sausa APF. Canine and feline intraocular neoplasms. Bospene EB. eds. In: Eye Cancer Research Progress. New York: Nova Biomedical Books, 2008; pp.49-98.
  • 3. Chandler HL, Barden CA, Newkirk KM, Kusewitt DF, Colitz CMH, Dubielzig RR. İmmunohistochemical analysis of uveal melanoma in cats and dogs. Invest Ophth Vis Sci 2008; 49(13): 70.
  • 4. Croix NL. “Ocular melanoma” Veterinary Medical Center of Long Island. http://www.vmcli.com/veterinary-articles-ocular-melanoma.htm. Erişim tarihi:16.07.2017.
  • 5. Duman R, Duman N, Duman R, Doğan M. İris nevüsleri ve melanomları: Ayırt edici parametreler. Acta Oncol Tur 2015; 48(1): 34-8.
  • 6. Finn M, Krohne S, Stiles J.Ocular melanocytic neoplasia. Comp Ophth 2008; 30(1): 1-8.
  • 7. Kalishman JB, Chappell R, Flood LA, Dubielzig RR. A matched observational study of survival in cats with enucleation due to diffuse iris melanoma. Vet Ophthalmol 1998; 1(1): 25-9.
  • 8. Ionaşcu I, Dinescu G, Anca CC. Iris melanoma in cats. Scientific Works-University of Agronomical Sciences and Veterinary Medicine, Bucharest Series C, Vet Med 2012; 58(4): 81-8.
  • 9. Pigatto JAT, Hünning PS, Almedia ACVR, Pereira FQ, Freitas LVRP, Gomes C, Scihiochet F, Rigon GM, Driemeier D. Diffuse iris melanoma in a cat. Acta Sci Vet 2010; 38 (4): 429-32.
  • 10. Planellas M, Pastor J, Torres MD, Pena T, Leiva M. Unusual presentation of a metastatic uveal in a cat. Vet Ophthalmol 2010; 13( 6): 391-94.
  • 11. Plummer CE, Kallberg ME, Olliver FJ, Gelatt KN, Brooks DE. Use of biosynthetic material torepair the surgical defect following excision of an epibulbar melanoma in a cat. Vet Ophthalmol 2008; 11(4): 250-4.
  • 12. Tilley LP, Smith FWK. Veteriner Hekimlikte 5 Dakikada Konsültasyon. Çeviren: Yeşildere T, Deprem O. İstanbul: Nobel Tıp Kitapevleri 2008; ss.1279-80.
  • 13. Wiggans KT, Reilly CM, Kass PH, Maggs DJ. Histologic and immunohistochemical predictors of clinical behavior of feline diffuse iris melanoma. Vet Ophthalmol 2016; 19(1): 44-55.

Primer Diffüz İris Melanom

Year 2019, Volume: 16 Issue: 2, 154 - 157, 08.08.2019
https://doi.org/10.32707/ercivet.595598

Abstract

Diffüz
iris melanom; enüklasyon, metastaz ve fonksiyonel görüş kaybı nedeniyle erken
tanısı oldukça önemli olan patolojik bir değişikliktir. Her iki gözü etkileyen
lokal ya da diffüz lezyon olarak ortaya çıkabilir. Sağaltımı hastanın yaşı,
klinik durumu, pigmentli alanın, sayı ve boyutunun artması, tümörün gelişim
oranı ve inatçı üveitis ile glokoma yol açma durumuna göre değişmektedir. Bu
olgu sunumunda yaklaşık bir yıldır sol göz, iris dokusunda pigmentasyon artışı,
göz küresinde buftalmus şikâyetleri ile getirilen sekiz yaşlı,
kısırlaştırılmamış, erkek, orta tüylü, tekir kedi değerlendirilmiştir. Klinik
muayenede, sol göz iris dokusunda diffüz bir kalınlaşma, koyu kahverengi
pigmentasyon, pupillar aralık kaybı ve sekonder glokom görülmüştür. Sağaltımda
göz küresi enüklasyon bulbi yöntemi ile uzaklaştırılarak histopatolojik
incelemeye alınmıştır. Histopatolojik inceleme sonucu iristeki pigmentasyonun diffüz
iris melanom olduğu tespit edilerek, hastanın bir yıllık takip süresince
herhangi bir doku ya da organa metastaz durumu ile karşılaşılmamıştır.

References

  • 1. Beton A, Healy LN, English RV, Bunch SE. Atypical limbal melanoma in a cat. J Vet Intern Med 1999; 13(4): 379-81.
  • 2. Baptista CS, de Sausa APF. Canine and feline intraocular neoplasms. Bospene EB. eds. In: Eye Cancer Research Progress. New York: Nova Biomedical Books, 2008; pp.49-98.
  • 3. Chandler HL, Barden CA, Newkirk KM, Kusewitt DF, Colitz CMH, Dubielzig RR. İmmunohistochemical analysis of uveal melanoma in cats and dogs. Invest Ophth Vis Sci 2008; 49(13): 70.
  • 4. Croix NL. “Ocular melanoma” Veterinary Medical Center of Long Island. http://www.vmcli.com/veterinary-articles-ocular-melanoma.htm. Erişim tarihi:16.07.2017.
  • 5. Duman R, Duman N, Duman R, Doğan M. İris nevüsleri ve melanomları: Ayırt edici parametreler. Acta Oncol Tur 2015; 48(1): 34-8.
  • 6. Finn M, Krohne S, Stiles J.Ocular melanocytic neoplasia. Comp Ophth 2008; 30(1): 1-8.
  • 7. Kalishman JB, Chappell R, Flood LA, Dubielzig RR. A matched observational study of survival in cats with enucleation due to diffuse iris melanoma. Vet Ophthalmol 1998; 1(1): 25-9.
  • 8. Ionaşcu I, Dinescu G, Anca CC. Iris melanoma in cats. Scientific Works-University of Agronomical Sciences and Veterinary Medicine, Bucharest Series C, Vet Med 2012; 58(4): 81-8.
  • 9. Pigatto JAT, Hünning PS, Almedia ACVR, Pereira FQ, Freitas LVRP, Gomes C, Scihiochet F, Rigon GM, Driemeier D. Diffuse iris melanoma in a cat. Acta Sci Vet 2010; 38 (4): 429-32.
  • 10. Planellas M, Pastor J, Torres MD, Pena T, Leiva M. Unusual presentation of a metastatic uveal in a cat. Vet Ophthalmol 2010; 13( 6): 391-94.
  • 11. Plummer CE, Kallberg ME, Olliver FJ, Gelatt KN, Brooks DE. Use of biosynthetic material torepair the surgical defect following excision of an epibulbar melanoma in a cat. Vet Ophthalmol 2008; 11(4): 250-4.
  • 12. Tilley LP, Smith FWK. Veteriner Hekimlikte 5 Dakikada Konsültasyon. Çeviren: Yeşildere T, Deprem O. İstanbul: Nobel Tıp Kitapevleri 2008; ss.1279-80.
  • 13. Wiggans KT, Reilly CM, Kass PH, Maggs DJ. Histologic and immunohistochemical predictors of clinical behavior of feline diffuse iris melanoma. Vet Ophthalmol 2016; 19(1): 44-55.
There are 13 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Aynur Demir 0000-0002-7856-2789

Publication Date August 8, 2019
Submission Date August 22, 2017
Acceptance Date May 25, 2018
Published in Issue Year 2019 Volume: 16 Issue: 2

Cite

APA Demir, A. (2019). Primer Diffüz İris Melanom. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 16(2), 154-157. https://doi.org/10.32707/ercivet.595598
AMA Demir A. Primer Diffüz İris Melanom. Erciyes Üniv Vet Fak Derg. August 2019;16(2):154-157. doi:10.32707/ercivet.595598
Chicago Demir, Aynur. “Primer Diffüz İris Melanom”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 16, no. 2 (August 2019): 154-57. https://doi.org/10.32707/ercivet.595598.
EndNote Demir A (August 1, 2019) Primer Diffüz İris Melanom. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 16 2 154–157.
IEEE A. Demir, “Primer Diffüz İris Melanom”, Erciyes Üniv Vet Fak Derg, vol. 16, no. 2, pp. 154–157, 2019, doi: 10.32707/ercivet.595598.
ISNAD Demir, Aynur. “Primer Diffüz İris Melanom”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 16/2 (August 2019), 154-157. https://doi.org/10.32707/ercivet.595598.
JAMA Demir A. Primer Diffüz İris Melanom. Erciyes Üniv Vet Fak Derg. 2019;16:154–157.
MLA Demir, Aynur. “Primer Diffüz İris Melanom”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, vol. 16, no. 2, 2019, pp. 154-7, doi:10.32707/ercivet.595598.
Vancouver Demir A. Primer Diffüz İris Melanom. Erciyes Üniv Vet Fak Derg. 2019;16(2):154-7.